R P Bruno and Associates
Writing for Technology
Our Portfolio
Published articles, scientific research papers, text book chapters and promotional materials
Published Articles
Dr. Robert Fisher
See a selective list of published articles from 2004-present.

Dr. Mansoor Amiji
See a selective list of published articles from 1994-present.

Robert Bruno
Automated Inspection and Cleaning of Fiber Optic Cable Connections, An Industry Breakthrough
Fiber optics cabling, a $5.9 billion industry, is the core of today's worldwide data communication networks and is the predominant media type for mission-critical data center links within Military/Aerospace, Telecom, Datacom, and Cable Manufacture/Assembly.

Steven Schwaitzberg MD, FACS is Professor and Chair of the Department of Surgery at the University at Buffalo School of Medicine and Biomedical Sciences. Previously he was chief of surgery at the Cambridge Health Alliance and Professor of Surgery at the Harvard Medical School. Dr Schwaitzberg has set a goal to provide laparoscopic training remotely for surgeons who may be located anywhere in the world by utilizing video conferencing in conjunction with a newly evolving “universal translator”. The coming together of these technologies will enable the trainer and the trainee to converse remotely, in real-time and in a wide range of languages.

TerraVerdae Bioworks Inc., A White Paper for Investors
Converting biomass into energy and polymer substitutes for existing petroleum derived products (plastics, etc) is playing an ever increasing role today in reducing our dependency on fossil fuels while at the same time focusing on developing solutions to the world’s most pressing problems related to greenhouse gas emissions, energy security and industrial sustainability

"Reducing the Effects of Lipid Oxidation" as it appeared in Nov-Dec 2012 issue of NutraCos (Milan, Italy) page 44-45

A Breakthrough in Microreactor Technology - New Technology Produces Nano -Suspensions with Continuous Flow Reactions
The PureNano Continuous Flow Microreactor is a novel manufacturing technology that enables continuous flow chemical reactions¹ involving solids as reactants or products for the production of stable nano-suspensions.

Printed in Transdermal Journal, September 2011
Biphasic Vesicles: A Novel, Lipid-Based, Topical Delivery System for Large-Molecule Drugs
Scientists recently demonstrated that biphasic vesicles—a novel, lipid-based, topical delivery
system—can deliver large-molecule or macromolecule drugs into the skin. Although challenging, success with biphasic vesicles offers the potential of needle-free administration of many pharmaceuticals, including biologics [1], that medical practitioners until now could administer only by injection.

Pulsating Aerosols Prove Highly Effective in Delivering Medications to the Sinuses
The PARI SINUS™ is an inhalation device that is designed to target drug delivery to the sinus cavities using a novel pulsating airflow technology. The paranasal sinuses are non-ventilated organs which, until now, have been difficult to deliver prescribed medication using conventional aerosol delivery systems.

HIGH ENERGY Impinging Jet Technologies FOR Continuous Crystallization of Non-water soluble Drug NANOSuspensions
Presented here is a novel technology (PureNanoTM) for continuous crystallization and large scale production of drug mirco- or nano- particles with tailored properties, in a highly efficient matter.

PureNano Continuous Crystallizer: A Breakthrough in Crystallization Technology Enables Continuous Manufacturing of Non-soluble Drug Suspensions
Featuring a pharmaceutical case study for oncology drug formulation with improved bioavailability and delivery capabilities

As seen in Pharmaceutical Online magazine, July 2010
Article: Dissolved Ozone In Pharmaceutical Water Systems Why Use And Measure Dissolved Ozone
Ozone is a naturally occurring triatomic form of oxygen (O3) and exists in the gas form in nature. Familiar sources of ozone are lightning in the atmosphere, the sun's UV in the upper stratosphere creating the infamous "ozone layer", and copy machines or laser printers. Ozone forms when oxygen comes in contact with ultraviolet (UV) energy wavelength of 185 nm. The UV energy splits the oxygen molecule which then reattaches to another oxygen molecule.

Comparison Testing of Competitive Portable Jet Nebulizer Systems with Two Inhaled Medications Shows a Wide Variability in Performance - A PARI Respiratory Equipment , Inc. White Paper

New Inhaled Liposomal Cyclosporine A Formulation Gives Hope For Lung Transplant Recipients
as seen in Pharmaceutical Online - The Magazine (10/09)

Using Particle Collisions For Mixing And Dispersion as seen in Chemical Processing
Achieving Optimal Particle Size Distribution in Inhalation Therapy as seen in Medical Design Technology

From The Lab To Commercial Production: The Challenge Of Scaling Up Homogenization Processes as seen in Lab Manager
Promotional Materials

Some Examples:

Financial Reports SEC 10K / 10Q Reports